Measuring the True ROI of GWAS Research

Citation Gap

ROI studies rely on patent citations, but citations miss when research influences innovation without explicit reference.

Spillover Gap

Metrics only count direct outcomes, but discoveries about one gene inform research on biologically related genes.

BioBERT Text Mining

Extract gene-disease mentions directly from patent text using biomedical language models—capturing actual content, not just citations.

→ Comprehensive patent-to-science linkage

KEGG Pathway Spillovers

Use biological pathway networks to measure how knowledge flows from discovered genes to related genes.

→ Quantifiable "distance" for spillovers